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Clinical research associate. Institute of Child Health, UK
CMC does not represent a specific disease, but rather a phenotypic presentation of a spectrum of Immunologic, Endocrinologic, Autoimmune disorders.
The unifying feature of these heterogeneous disorders is impaired cell-mediated immunity against Candida species.
Martine PERGENT, Vice President IPOPI, the International Patient Organisation for Primary Immunodeficiencies
Primary Immunodeficiencies (PID) are a group of genetic disorders caused when the immune system does not work properly. PIDs are life threatening conditions that lead to severe infections and high rate of mortality when not diagnosed and treated properly. Considering the prevalence of those conditions, around 600.000 people in Africa have their lives impacted by these chronic conditions. 99% remain undiagnosed and untreated.
The PID environment in the Africa is challenging and many factors hinder further progress including poor medical and healthcare infrastructure, low diagnosis rate, lack of awareness and medical expertise as well as financial and socio-economical issues. There are not many patients diagnosed and an added difficulty is to identify volunteers to engage into patients organisations.